An explosion occurred today in a building in Manhattan's East Harlem neighborhood, collapsing at least part of the structure and injuring at least 11.

Plumes of thick smoke have engulfed the area around the building at 116th Street and Park Avenue after residents reported hearing a loud explosion around 9:30 a.m.

Shattered windows in nearby shopfronts show the extent of the explosion, which may have been caused by a gas leak, according to ABC station WABC.

A fire was reported in the building and the structural integrity of the structure may be compromised, with witnesses reporting a partial roof collapse. There are no reports of anyone trapped inside at this time.

Harlem Hospital told WABC they are treating one patient with "heavy trauma" and expecting one more. The other victims reportedly suffered minor injuries. An FDNY source told ABC News that one burn victim in very critical condition.

More to follow!